- Desalted deep-sea water improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus
- Naoaki Harada, Juan Zhao, Hiroki Kurihara, Naomi Nakagata, Kenji Okajima
- Translational Research
After an Investigation Committee on Scientific Misconduct was formed at Nagoya City University to investigate 19 articles written by Drs. Naoaki Harada and Kenji Okajima, the committee brought one article, published in Translational Research, to our attention.The committee concluded that Figures 4D, 4E, 4G and 4H in Translational Research(Harada et al., 2011) were derived from the same photograph as Figures 8D, 8E, 8G and 8H in Journal of Pharmacology and Experimental Therapeutics (Narimatsu et al., 2009). While Figures D and G represent control data in both articles, Figures 4E and 4H and Figures 8E and 8H represent data from two different sets of animals treated with either desalted deep sea water or donepezil, respectively. The Nagoya City University Committee concluded that Figure 4 in Translational Research (Harada et al., 2011) contains fabricated data. After the Committee pointed out these fabrications to the authors, they replaced Figures 4A-4I and an Erratum was published inTranslational Research (Transl. Res., 158 (2011) 387). However, the Committee has informed us that they have been unsuccessful in confirming that the new figures are the appropriate ones. Attempts to contact Drs. Harada and Okajima were made through the Nagoya Committee, and the authors declined to respond.